BASF to launch new azole fungicide for 2019

Agrochemicals giant BASF is set to launch a new “blockbuster” azole cereal fungicide as early as 2019 and then a blackgrass herbicide with a new mode of action early next decade.

The fungicide, called Revysol, is likely to be used as a partner to help slow down fungicide resistance, while the blackgrass killer could be the biggest breakthrough in grassweed control for more than 10 years.

Markus Heldt, president of BASF Crop Protection, said the fungicide is the German group’s most exciting near-term launch and is needed to counter increased disease problems.

“This is our largest-ever launch and will be in more than 50 countries and in more than 60 crops in a difficult environment,” he said at a group briefing in Germany this week.

This azole fungicide is claimed to have a high level of efficacy and is likely to be partnered with SDHI fungicides to control troublesome wheat diseases such as septoria and yellow rust.

Blackgrass killer

The new grassweed killer under development is a residual pre-emergence product and will be aimed at the core cereal herbicide market in Europe.

 “This herbicide has a new mode of action in cereals in the UK and we are confident it has a good regulatory profile,” Mr Heldt told Farmers Weekly at the group’s headquarters in Ludwigshafen, on the River Rhine about 50 miles south of Frankfurt.

He said it would be a big product for BASF and a very important one for UK farmers.

“The fastest it may be available would be autumn 2020, but it is more likely to be available in 2021 or 2022,” he added. Mr Heldt clarified that the herbicide will not offer a completely new mode of action, but a different mode of action to those currently seen in UK cereal production.

New azole fungicide

Looking at the fungicide, independent expert Bill Clark said Revysol has the eradicant properties of the older azoles seen some 10-15 years ago before their efficacy started to decline, especially against septoria.
“This is important for the whole industry, and will be a partner for all SDHIs, and SDHIs which are coming,” added Mr Clark, who is technical director at crop consultant Niab.

Older azoles such as prothioconazole and epoxiconazole have declined in efficacy against septoria in wheat over the past decade, but it is hoped this new azole could be used with the new generation of SDHIs launched in the past five years and could delay fungicide resistance.

“Revysol is better than prothioconazole and epoxiconazole as septoria has not adapted to it,” he said.

Azoles have been the backbone of fungicide programmes since the mid-1970s due to their broad spectrum of disease control against septoria, rusts and fusarium, and their systemic action give good eradicant and protective properties.

Good efficacy

Rolf Reinecke, head of BASF’s global marketing for fungicides, said the new product showed better efficacy compared with older azoles and showed no side-effects.

“We have a highly active fungicide with a favourable profile from a regulatory point of view,” he added.

Mr Reinecke said the first launch of the new azole is set for the 2018-19 season, which for the UK would mean spring 2019, and it could be the first new azole to be launched since prothioconazole more than 10 years ago.

The development comes at a time when the use of azoles is coming under pressure due to fears they could be classed as endocrine disruptors, meaning they could interfere with human hormone levels.

This could mean older azoles might be restricted or even banned in the future, so Mr Reinecke is keen to stress the new azole has a good regulatory profile.

Fungicide resistance

Most widely used azoles such as prothioconazole, epoxiconazole, tebuconazole and metconazole are of the triazole sub-group, as is Revysol.

However, Rosie Bryson, team lead for BASF’s arable fungicide development, says Revysol is a isopropanol type of triazole – different from the other four – and this may help to slow down the build-up of fungicide resistance.

“Revysol has so far given good control of shifted isolates of septoria, and this could be useful in reducing the mutation of the disease,” she said.

Although there are only low levels of mutations of septoria from the use of new SDHIs, growers are urged to continue using three modes of action against septoria as part of a resistance-management strategy.

This means using SDHIs in conjunction with azoles and also a multi-site fungicide such as chlorothalonil.