As agrochemical prices skyrocket, so do investments in biological alternatives

Date:02-22-2022

By Jack Ellis

Startups developing biological inputs for crops raised just over $892 million worldwide last year, according to preliminary data from AgFunder.

That’s well over double their total funding haul for the previous year – indicating just how much interest in the space has grown.

Please note that this is an upward revision of AgFunder figures first quoted by Reuters earlier this month. The data are adjusted using a model of how they will appear 12 months into the future based on historical trends, to take predicted reporting lags into account. As such, they may differ from earlier published versions of the same data.

Below, AgFunder lists the top 15 biologicals funding deals from 2021, by US dollar amount raised.

AgFunder has included all private ventures working on a variety of biological crop inputs, including:

• Biofertilizers

• Biopesticides

• Biofungicides

• Biostimulants

• Other biological controls

Top 15 biological inputs deals, FY2021

Company	Country	Amount raised	Stage	Deal date
Pivot Bio	US	$430 million	D	Jul
AgBiome	US	$116 million	D	Sept
Anuvia Plant Nutrients	US	$103 million	C	Feb
Invaio Sciences	US	$88.9 million	C	May
Invaio Sciences	US	$50 million	Debt	Oct
Vestaron Corporation	US	$18.3 million	B	Feb
BioPhero	Denmark	$16.8 million	A	Mar
Gaiago	France	$15.4 million	A	Jul
Groundwork BioAg	Israel	$11 million	A	May
Micropep Technologies	France	$10.1 million	A	Aug
Kula Bio	US	$10 million	Seed	May
Provivi	US	$10 million	C	Feb
AgroSustain	Switzerland	$5.19 million	A	Jul
Lucent BioSciences	Canada	$4.2 million	Seed	Nov
BigSIS	UK	$2.05 million	Seed	Oct

By geography, of the top 15 deals:

• Eight (53%) involved companies headquartered in the US.

• France is second-placed with two deals (13%).

• Canada, Denmark, Israel, Switzerland, and the UK played host to one deal each.

By far the biggest deal in the biologicals space last year — and among the top 20 in agrifoodtech overall — was Pivot Bio‘s $430 million Series D round in July, which was co-led by DCVC and Temasek.

Pivot Bio is one of several startups offering an alternative to conventional nitrogen-based fertilizers by ‘programming’ microbes in the soil so that they produce more of the element in situ.

Another company on  the above list working on a similar solution is Kula Bio, which leverages the nitrogen-storing bacteria Xanthobacter autotrophicus. It raised $10 million in seed funding in May.

Second-placed AgBiome is focused on pest and disease control: it screens the natural world for microbes which might be suitable for such purposes — its initial products are fungicides — and it scored $116 million for its September Series D round.

Chemical prices through the roof

There are two main drivers behind this explosion of investor interest in biological inputs.

On the one hand, there’s the combination of environmental, regulatory, and consumer pressures pushing the agricultural industry away from excessive use of, and reliance on, chemical inputs.

Synthetic, chemical-based fertilizers and pesticides are typically sprayed imprecisely onto fields. Excess amounts leach into the surrounding environment, and can oxidize, contributing to greenhouse gas emissions.

Biological alternatives, it is argued, are more targeted in their action and have less of a negative impact on their surroundings.

The second major driver comes from the market. Partly due to Covid-19 supply chain disruptions, the prices of various chemicals are going through the roof.

This is particularly the case when it comes to synthetic nitrogenous fertilizers, which are mostly produced from raw materials like ammonia and urea. The prices of these commodities soared during 2021 and into the early part of this year, hitting multi-year highs in some cases.

Herbicide and pesticide prices are also on a rapid upward trend.

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