The sulfonylurea herbicide has become the hot spot for its advantages in efficiency and environmental-friendly. By the end of 2009, 24 products have gained approval in China with 527 single formulation producers and 591 mixture formulation producers. Many of the products have gained considerable popularities among the growers and distributors by their high activities and selectivities. The bensulfuron-methyl for rice, the nicosulfuron for corn, the tribenuron-methyl for wheat and chlorimuron-ethyl for soybean play dominant roles in their fields. However, the slow development of new products, weak productivities in its intermediates and inappropriate of its applications have constrained its development in China.
Redundant construction on certain kinds of products has appeared in recent years. For example there are dozens of manufacturers for nicosulfuron and bensulfuron-methyl in China, more than 500 registrants have received approvals for bensulfuron-methyl mixtures, which implied signs of overcapacity. Thus the redundant production should be reduced by developing new molecules. Species such as mesosulfuron-methyl, foramsulfuron, idosulfuron-methyl, flupyrsulfuron-methyl-sodium, flucetosulfuron and azimsulfuron are having promising prospects. Furthermore, development on some combinations and new formulations should be valued as well.
Pesticide injures led by inappropriate usage have result several bans and restrictions of some sulfonylurea products. Herbicide products containing metsulfuron, chlorsulfuron and ethametsulfuron have been banned or restricted in China, thus the injury problems have become another constraint for the industry. The problems can be solved by more training on the growers as well as improving their safeties by equipped advanced spraying instrument.
The intermediate, 2-Amino-4,6-dimethoxypyrimidine, has become an important material of the products as more than 20 of its derivates are the ingredients of the products. Yet diversity of its synthesis routes has obstructed the industrialized and scale production. China should find the route suited to its conditions while improving process performance and productivity.
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