CRISPR: EU focus on organic farming will not get us where we need to be

Date:07-05-2021

By Rudi Ariaans & Ferdinand Los

Our global output in agriculture has grown to an astounding 3 billion metric tons of crops – which has been mirrored by the inputs needed. Last year alone, we used 187 million metric tons of fertilizers, of which 70% was wasted and either ran off to underground waters or volatilized into the atmosphere. At the same time, 4 million metric tons of pesticides were applied, and agriculture accounted for 70% of the freshwater used globally. Tellingly, agriculture is now responsible for 24% of global greenhouse emissions.

An even more ominous figure was captured by a recent study by scientists from Cornell, Maryland, and Stanford universities, which found that global agricultural productivity has declined by about 21% in the last 60 years as a result of climate change. Add to that the expected population growth over the next decades, and you begin to undertsand that even with the improvements in yields we have seen over the last few decades, breeders cannot continue to guarantee production for all people. That’s why we need gamechangers in the form of novel methods and technologies that can help us – in consumption patterns, farming techniques, and biotech innovation.

Is the EU’s Farm to Fork Strategy realistic to increase sustainable food systems?

In the EU, the European Commission has pledged itself to the Farm to Fork Strategy, which is centered on organic farming. In this approach, 25% of the EU’s agricultural land will be used for organic farming by 2030. And while the European Commission acknowledges that innovations in areas like biotechnology can play an important role, regulation around novel genomic techniques is still restrictive.

Organic farming can definitely contribute to sustainability, but negative indirect effects such as additional land use needed for this method of farming are often overlooked. An organic farm will have an approximately 50% lower yield in comparison to non-organic farming. A massive transition to organic farming will decrease the pressure on our ecosystems in Europe, but can have substantial negative spill-over effects. Already we see that approximately 16% of global deforestation is linked to consumption in the EU.

As organic farming has a lower yield than non-organic farming, we would need almost twice as much arable land to grow the same amount of food. If we do not tackle this issue, the Farm to Fork Strategy may actually result in less sustainable, rather than more sustainable, food systems.

CRISPR will help us develop the varieties we need more quickly and efficiently

Novel breeding techniques have been instrumental in maximizing agricultural productivity, profitability, and sustainability. The technique that has generated most publicity — culminating in a Nobel Prize in Chemistry for Emmanuelle Charpentier and Jennifer Doudna — is CRISPR, which scientists can use to adjust or rewrite DNA in a highly precise manner.

These edits are based on research that has been going on for decades to understand the molecular processes underlying genetic traits. Where these kinds of adjustments would traditionally take between seven and 10 years (if possible at all), they can now be done within two to four years. Owing to this, CRISPR has revolutionized how we can breed plants and make our food systems sustainable in the face of climate change and population growth.

An example is speeding up the development of varieties that need less fertilizer, water, or pesticides due to the targeted editing of traits. Taking into account we need these new varieties to decrease the pressure on our natural ecosystems while maintaining food security, the most obvious step to reach the goals in a reasonable timeframe, using an available technology, is CRISPR.

The key strength of CRISPR-based breeding is that it allows for faster and more targeted development of crop varieties. After several years of development, CRISPR is a technology mature enough to deliver today the plants that we need for the future, in a safer and more controlled manner than other approved genetic modification (GM) approaches such as mutagenesis.

As organic farming prohibits the use of synthetic pesticides, we urgently need to develop varieties that are hardier and less prone to pests and pathogens. And because organic farming generally uses more land for the same yield, we urgently need crop varieties with higher yields, to limit the additional arable land we need.

Additionally, these new varieties could decrease water, land, and chemical use in traditional, non-‘organic’ farming practices, too. But our traditional breeding approaches will not get us there in time, and CRISPR offers us the chance to accelerate the development of new varieties. Only with CRISPR can we generate crop varieties that would meet sustainability demands from organic and non-organic farming within the timeframe needed.

So it’s a clear win-win, right?

EU says no

Unfortunately, not. For this innovative tandem of organic farming and innovative biotechnology we require legislative change in the EU.

While the rest of the world is rapidly adopting CRISPR technology and solving these issues, the European Court of Justice ruled in 2018 that organisms altered by means of site-directed mutagenesis, like CRISPR, are included in the EU’s definition of a genetically modified organism (GMO.)

The implications of this ruling continue to be felt today, as it means the size or type of alteration to the genetic material is irrelevant. If there is mutagenesis — random or directed, big or small — the organism is legally deemed a GMO, and commercializing it on the European market is effectively impossible. 

Read the complete article at www.agfundernews.com.