US EPA proposes registration of new agricultural fungicide active ingredient inpyrfluxam

Date:06-08-2020

U.S. EPA is opening a 30-day comment period on its proposal to register the new active ingredient inpyrfluxam.

Inpyrfluxam is a pyrazolecarboxamide fungicide proposed for foliar and seed treatment agricultural uses. The chemical provides protection against Rhizoctonia species causing seed decay, seedling damping‐off, and root rot.

The uses proposed for inpyrfluxam are:

- seed treatment of crop group 6 (legume vegetables), crop group 15 (cereal grains), crop subgroup 20A (rapeseed), dry seeded rice, and sugar beet;

- foliar application to apple, peanut, soybean, and sugar beet; and

- in-furrow soil application at planting to corn (field, sweet, and pop).

Inpyrfluxam adds a new mode of action against key fungal pests that can cause high yield losses to soybean and sugarbeet crops. It is also likely to play a role in fungicide resistance management on those crops. On other crops (apple, corn, peanut and rice), inpyrfluxam appears to be comparable to currently available alternative fungicides.

Human health risk estimates for inpyrfluxam are not of concern for all potential routes of exposure, including dietary, occupational and aggregate. The proposed registration contains several measures to mitigate ecological risks associated with the proposed uses.

EPA reviewed inpyrfluxam jointly with Canada’s Pest Management Regulatory Agency (PMRA), with Mexico as an observing member. U.S. tolerances and Canadian MRLs are being harmonized as part of the joint review process. PMRA has not yet published its proposed decision document.

The proposed registration includes four products: one technical grade and three end-use products.

This proposal is included in docket EPA-HQ-OPP-2018-0038 at regulations.gov. Comments are due on or before July 7, 2020