Canada to re-evaluate pyriproxyfen
Date:03-31-2017
The Health Canada’s Pest Management Regulatory Agency (PMRA) plans to re-evaluate insect and mite growth regulator, pyriproxyfen.
Pyriproxyfen is registered in Canada for the control of a variety of insect and mite pests in greenhouse food and non-food crops, various indoor structures and furniture as well as on companion animals (dogs and cats). As of 4 January 2017, there are one technical grade product, three manufacturing concentrates, two commercial products and 32 domestic class end-use products containing pyriproxyfen registered in Canada.
Under the authority of section 16 of the Pest Control Products Act, all registrants of pyriproxyfen were notified of the initiation of the re-evaluation of pyriproxyfen. Following this, the registrant of pyriproxyfen technical grade active ingredient in Canada indicated support of all uses included on the labels of commercial and domestic class products in Canada.
The re-evaluation project plan below outlines the timeline, the anticipated areas of focus for the risk assessments, and the data requirements for the re-evaluation of pyriproxyfen.
Re-evaluation Project Plan
▶ Anticipated Re-evaluation Timeline
The re-evaluation of pyriproxyfen is defined as a Category1 as described in Regulatory Directive DIR2016-04, Management of Pesticides Re-evaluation Policy, which was adopted on 1 December 2016. However, because this re-evaluation was initiated prior to the publication of DIR2016-04, the proposed re-evaluation decision for pyriproxyfen is anticipated to be published for consultation by July 2019. The re-evaluation timeline may be updated if, during the risk assessment, PMRA identifies additional areas of focus that should be considered.
▶ Human Health Risk Assessment
Existing assessments with minor updates are considered to be adequate to support the re-evaluation of pyriproxyfen for most review areas.
▶ Environmental Risk Assessment
Existing assessments with minor updates are considered to be adequate to support the re-evaluation of pyriproxyfen for most review areas.
▶ Value
The value of pyriproxyfen will be considered. The viability of alternatives will be examined for certain uses if risks of concern requiring mitigation are identified.
Data Requirements
PMRA has identified the need for the technical registrant to provide data for pyriproxyfen related to chemistry and toxicology. Relevant data/studies have been requested from the technical registrant. A summary of the data call-in is found in PMRA’s Public Registry, found online at
Pesticide Product Information Database.