Caprotec bioanalytics signed research agreement with Bayer CropScience

Caprotec bioanalytics GmbH announced that it has initiated a research collaboration with Bayer CropScience. Under the collaborative research agreement, caprotec will use its proprietary CCMS (Capture Compound Mass Spectrometry) technology to profile the interactions of one of Bayer CropScience's undisclosed new active ingredients in the relevant biological system.

"We are very excited about the opportunity to collaborate with Bayer CropScience applying our CCMS technology in the field of agrochemicals to discover the target protein and the mode of action, allowing subsequent structural optimization," said Dr. Hubert Koster, CEO of caprotec. 
 
"CCMS permits the direct isolation of the agrochemical-specific subset of proteins from a complex biological sample in an unbiased way. Due to the functional enrichment of the proteins and their covalent attachment to the Capture Compounds, CCMS also identifies low abundant and weakly interacting proteins. Direct interaction of the small molecules to the proteins can be confirmed as well. The CCMS process is carried out in solution so that even membrane proteins like ion channels and GPCRs from whole intact cells can be identified. CCMS fills a crucial technological gap in the important field of functional proteomics," continued Dr. Koster.
 
"We were impressed by the results of a CCMS pilot study, and are now looking forward to a continuation of our successful collaboration with caprotec," stated Dr. Alexander Klausener, Head of Research, Bayer CropScience.