Anvisa opens public consultation on Isopyrazam in Brazil

The Brazilian National Health Surveillance Agency (Anvisa) has opened a period for public comments on the pesticide Isopyrazam. 

This fungicide is the active ingredient in various Syngenta products worldwide, including Rikali and Reflect. The outcome of this public consultation may determine the future of the product registration process in Brazil.

Isopyrazam belongs to the group of SDHIs (succinate dehydrogenase inhibitors), which targets complex II (or succinate dehydrogenase) in the mitochondrial respiratory chain, disrupting the flow of electrons and thus altering cellular respiration. SDHI group fungicides function by blocking a crucial step in fungal respiration provided by succinate dehydrogenase (SDH).

FRENCH ALERT

A team of French researchers argues that SDHI family fungicides are toxic not only to fungi but also to earthworms, bees, and human cells. Pierre Rustin, a researcher at Inserm (National Institute of Health and Medical Research) led the team, which also published a study in the scientific journal Plos One. In the research, they highlight the toxicity of eight SDHI family fungicides (Flutolanil, Fluopyram, Boscalid, Fluxapyroxad, Penflufen, Penthiopyrad, Isopyrazam, and Bixafen).

Those interested in supporting or contesting the market entry of the product can access the suggested draft and the form for consideration through the Anvisa website: http://antigo.anvisa.gov.br/consultas-publicas#/

(Editing by Leonardo Gottems, reporter for AgroPages)