Plant Health Care plc announces new products submitted for regulatory approval

Plant Health Care plc has submitted applications to the regulatory agencies in Brazil for approval to commercialize the Company's newest products, PHC279 and PHC949 for use on major crops in Brazil. In the latest season, Brazil had 8.3 million hectares of sugar cane under cultivation and more than 2.2 million hectares of coffee. PHC279 was submitted for the control of sugar cane orange rust (Puccinia kuehnii) and coffee leaf rust (Hemileia vastatrix).

PHC279 is the active ingredient in the Company's product Saori^®, which is already used in Brazil for the prevention and treatment of soybean diseases. PHC949 was submitted as a seed treatment for the control of root-lesion nematode (Pratylenchus brachyurus) in soybean. It is a novel product that amplifies a plant's natural defense against damaging nematodes (a "bionematicide"), increasing plant health and yield in a variety of crops.

For 2022/23, the soybean harvested area in Brazil is forecast to be 42.9 million hectares. Results from field studies show PHC949 may provide control of harmful nematodes comparable to the traditional chemical nematicides and superior to current biological products. Both productsare derived from the Company's PREtec technology platform (Vaccines for Plants™).

Derived from natural proteins, PREtec is an environmentally friendlytechnology which stimulates crop growth and ability to withstand a variety of abiotic stresses as well as to improve disease control, plant health and yield. PREtec is compatible with mainstream agricultural practices. Saori was the first PREtec product fully launched in Brazil in late 2021 generating revenue of $0.8 million in the six months to 30 June 2022.

The Brazilian authorities do not commit to a specific timeline for granting regulatory licenses. However, the Company expects the review to start soon and given the accelerated review previously granted to Saori, anticipates regulatory licenses will be granted in 1-2 years.