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Holista registers anti- mosquito biopesticide in Malaysiaqrcode

Aug. 31, 2011

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Aug. 31, 2011

Biotech research company Holista CollTech Limited and its partner EntoGenex Industries have registered with Malaysian authorities MOUSTICIDE™, the first approval by any country for the bio-pesticide which starves mosquito larvae to death without harming humans.

MOUSTICIDE™ combines Trypsin Modulating Oostatic Factor (TMOF), a protein molecule found in mosquitoes whose genes are first inserted into yeast cells (Pichia pastoris) to increase their mass, with a widely used bio-pesticide, Bacillus thuringienis israelensis (“Bti”).

The yeast cells containing TMOF, which disrupts the ability of larvae to digest, are killed in very high temperatures before being applied to water bodies to facilitate control of mosquito breeding at relatively low costs.

HRH Tunku Naquiyuddin, EntoGenex’s Chairman, said MOUSTICIDE™ is a major innovation in bio-pesticide which combines safety, efficacy, and cost-effectiveness to significantly lower mosquitoes’ breeding rates.

Holista and EntoGenex are exploring collaborations with leading philanthropic organizations like the Bill & Melinda Gates Foundation, Carter Trust, Rockefeller Foundation and Grameen Foundation to facilitate worldwide adoption of MOUSTICIDE™ to eradicate mosquito-borne diseases such as malaria, dengue and chikungunya.

More than 700 million people are affected by mosquito-borne diseases globally, including South America, Africa – where 90% of the continent is affected by malaria – and parts of Asia, where dengue is rife.

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