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US/Canadian approvals for Rynaxypyrqrcode

May. 14, 2008

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May. 14, 2008
DuPont has received US and Canadian approvals for its chlorantraniliprole-based insecticides, Altacor and Coragen, for use on a range of fruit and vegetable crops. They are the first registrations in major western markets, following introductions in the Philippines, Indonesia and Romania last year.
Chlorantraniliprole, which DuPont has trade-marked as Rynaxypyr, is undergoing joint reviews in the EU, Australia and New Zealand. It is regarded by the US EPA as the first active ingredient to be undergoing a global registration. The US and Canadian approvals represent a “key DuPont milestone”, the company says. “Progress is being made on registrations in many other countries,” it adds.
Altacor is a 35% water-dispersible granule formulation for use on grapevines, pome and stone fruit, cotton and potatoes. It is recommended for use in the US at 2-4.5 oz/acre (138-311 g/ha). Coragen is a 1.7 lb/gallon (200 g/litre) suspension concentrate for vegetable crops, including brassicas, cucurbits, lettuces, tomatoes and peppers. Application rates range from 2 fl oz/acre (148 ml/ha) to 7.5 fl oz/acre depending on the crop and pests present. The insecticides are effective against “almost all economically important Lepidoptera” as well as leafminers and various coleopteran pests, according to DuPont.
While establishing tolerances for chlorantraniliprole on the crops for which it is approved, the EPA has also set a temporary tolerance for rice in connection with emergency exemptions in Texas and Louisiana. The states were granted exemptions to allow the use of the seed treatment, Dermacor X-100, for the control of rice water weevils (Lissorhoptrus oryzophilus). The rice tolerance is set to expire on December 31st 2011.
Chlorantraniliprole is the first compound from a new chemical class, the anthranilic diamides. It acts on insect ryanodine receptors, which play a critical role in muscle function. It provides “unprecedented” larval control, and is “frequently one or two orders of magnitude more potent” than commercial standards, DuPont says. The insecticide also has ovicidal activity against eggs laid on treated surfaces. The active ingredient penetrates leaf surfaces and is effective against chewing and sucking insects on either side.
Due to its novel mode of action, chlorantraniliprole is effective against pests that are resistant to other chemical classes, DuPont points out. The insecticide has minimal impact on beneficial species, making it ideal for use in IPM programmes, the company adds. Chlorantraniliprole displays “very low toxicity” to mammals due to the structural difference between insect and mammalian ryanodine receptors.
Source: DuPont

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