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Battle lines drawn as EU court weighs fate of gene-edited cropsqrcode

Jul. 23, 2018

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Gene editing in agriculture takes center stage this Wednesday when Europe’s highest court rules in a case that could determine the fate of the technology that is already making waves in the field of medicine.

Professor Wendy Harwood poses for a photograph with barley plants that have undergone gene editing at the John Innes Centre in Norwich, Britain, May 25, 2016. REUTERS/Stuart McDill/File Photo

The European Union has long restricted the use of genetically modified organisms (GMOs) widely adopted around the world, but there is legal uncertainty as to whether modern gene editing of crops should fall under the same strict GMO rules.

The European Court of Justice (ECJ) will rule whether the use of genetic mutation, or mutagenesis, which is now exempt from GMO rules, should differentiate between techniques that have been used for decades and the new gene-editing technology.

The biotech industry argues that much of gene editing is effectively little different to the mutagenesis that occurs naturally or is induced by radiation - a standard plant breeding method since the 1950s.

But environmentalists, anti-GM groups and farmers concerned about the potential environmental and health impacts of all genetically engineered products fear that allowing gene editing would usher in a new era of “GMO 2.0” via the backdoor.

Gene editing with the CRISPR/Cas9 tool and other techniques has the potential to make hardier and more nutritious crops - as well as offering drug companies new ways to fight human disease.

U.S biotech firm Calyxt, for example, has gene edited soybeans to produce healthier oil with no trans fats and it is growing 17,000 acres of its new design across the U.S. Midwest this year.

Big agrochemical specialists such as Germany’s Bayer and U.S. firm DowDuPont are also stepping up investment in the technology.

The case before the ECJ was brought by a group of French agricultural associations that want the existing EU exemption for plant varieties obtained via mutagenesis to be restricted to long-standing conventional techniques.

50 TIMES FASTER

While older GMO technology typically adds new DNA to a crop or animal, gene editing can cause a mutation by changing a few pieces of DNA code. It works with great speed and precision, like the find-and-replace function on a word processor.


The main courtroom of the European Court of Justice is pictured in Luxembourg January 26, 2017. REUTERS/Francois Lenoir/File Photo

“Anything you can do by standard mutagenesis you can do 10 or maybe 50 times quicker,” said Johnathan Napier, who is leading a trial at Rothamsted Research which has involved the sowing of the first gene-edited crops in Britain.

He said the first wave of gene-edited crops may involve removing harmful elements from food, such as developing peanuts without peanut allergens or castor bean oil without ricin toxin.

But critics say the technology is not yet proven safe - an argument that may have gained weight this week after research suggested gene editing can cause risky collateral DNA damage.

So far, the signs are that the court may lean toward the biotech industry’s view. ECJ advocate general Michal Bobek advised in January that organisms could be exempt from GMO rules if they did not have added foreign DNA.

The advocate general’s view is not binding but is usually followed by ECJ judges.

John Brennan, secretary general of the biotech industry group EuropaBio, believes gene-edited crops will bring consumer and environmental benefits, as well as keeping Europe at the forefront of a technology important for jobs and growth.

“A clearer regulatory status is essential for communicating and understanding the opportunities that these tools and products present,” he said.

The first wave of gene-edited crops involve removing potentially harmful elements, such as the allergens in peanuts or ricin toxin in castor bean oil, said Napier at Rothmsted.

Environmental groups see things very differently.

“We’re talking about genetic engineering and that should be regulated under GMO law,” said Franziska Achterberg of Greenpeace.

Friends of the Earth, which helped bring the original case in France, contends that failure to regulate gene editing could cause permanent damage to Europe’s food sector.

Some retail groups that have been working to produce and market non-GMO food have also expressed concern.

Currently, strict rules mean only one GM crop, a variety of maize, is grown in Europe and while the EU allows the import of others they are exclusively used as animal feed.

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